- 产品信息
商品描述
靶点-Target
EphB6
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
111kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of EphB6 expressed in E. Coli.
特异性
EphB6 Monoclonal Antibody detects endogenous levels of EphB6 protein.
基因名称
EPHB6
蛋白名称
Ephrin type-B receptor 6
别名
EPHB6;Ephrin type-B receptor 6;HEP;Tyrosine-protein kinase-defective receptor EPH-6
Organism-1
Human
基因ID-1
2051
SwissProt-1
O15197
Organism-2
Mouse
SwissProt-2
O08644
背景
This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
细胞定位
Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted .





