FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EphB2
反应性
Human
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
117kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of EphB2 (aa17-200) expressed in E. Coli.
特异性
EphB2 Monoclonal Antibody detects endogenous levels of EphB2 protein.
基因名称
EPHB2
蛋白名称
Ephrin type-B receptor 2
别名
EPHB2;DRT;EPHT3;EPTH3;ERK;HEK5;TYRO5;Ephrin type-B receptor 2;Developmentally-regulated Eph-related tyrosine kinase;ELK-related tyrosine kinase;EPH tyrosine kinase 3;EPH-like kinase 5;EK5;hEK5;Renal carcinoma antigen NY-REN-47
Organism-1
Human
基因ID-1
2048
SwissProt-1
P29323
Organism-2
Mouse
SwissProt-2
P54763
背景
This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple tr
细胞定位
Cell membrane; Single-pass type I membrane protein. Cell projection, axon . Cell projection, dendrite .
