FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EphA8
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
111kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of EphA8 (aa70-150) expressed in E. Coli.
特异性
EphA8 Monoclonal Antibody detects endogenous levels of EphA8 protein.
基因名称
EPHA8
蛋白名称
Ephrin type-A receptor 8
别名
EPHA8;EEK;HEK3;KIAA1459;Ephrin type-A receptor 8;EPH- and ELK-related kinase;EPH-like kinase 3;EK3;hEK3;Tyrosine-protein kinase receptor EEK
Organism-1
Human
基因ID-1
2046
SwissProt-1
P29322
Organism-2
Mouse
SwissProt-2
O09127
背景
This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection . Early endosome membrane . Undergoes clathrin-mediated endocytosis upon EFNA5-binding and is targeted to early endosomes. .
