- 产品信息
商品描述
靶点-Target
EphA3
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
110kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of EphA3 (aa751-983) expressed in E. Coli.
特异性
EphA3 Monoclonal Antibody detects endogenous levels of EphA3 protein.
基因名称
EPHA4
蛋白名称
Ephrin type-A receptor 4
别名
EPHA4;HEK8;SEK;TYRO1;Ephrin type-A receptor 4;EPH-like kinase 8;EK8;hEK8;Tyrosine-protein kinase TYRO1;Tyrosine-protein kinase receptor SEK
Organism-1
Human
基因ID-1
2043
SwissProt-1
P54764
Organism-2
Mouse
SwissProt-2
Q03137
背景
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density membrane . Early endosome . Cell junction, adherens junction . Clustered upon activation and targeted to early endosome. .





