FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EHMT1
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
141kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of EHMT1 expressed in E. Coli.
特异性
EHMT1 Monoclonal Antibody detects endogenous levels of EHMT1 protein.
基因名称
EHMT1
蛋白名称
Histone-lysine N-methyltransferase, H3 lysine-9 specific 5
别名
EHMT1;EUHMTASE1;GLP;KIAA1876;KMT1D;Histone-lysine N-methyltransferase EHMT1;Euchromatic histone-lysine N-methyltransferase 1;Eu-HMTase1;G9a-like protein 1;GLP;GLP1;Histone H3-K9 methyltransferase 5;H3-K9-HMTase 5;Lysine N-methy
Organism-1
Human
基因ID-1
79813
SwissProt-1
Q9H9B1
Organism-2
Mouse
SwissProt-2
Q5DW34
背景
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
细胞定位
Nucleus. Chromosome. Associates with euchromatic regions.
