FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EGF
反应性
Human
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
134kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human EGF expressed in E. Coli.
特异性
EGF Monoclonal Antibody detects endogenous levels of EGF protein.
基因名称
EGF
蛋白名称
Pro-epidermal growth factor
别名
EGF;Pro-epidermal growth factor;EGF
Organism-1
Human
基因ID-1
1950
SwissProt-1
P01133
Organism-2
Mouse
SwissProt-2
P01132
背景
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],
细胞定位
Membrane; Single-pass type I membrane protein.
