- 产品信息
商品描述
靶点-Target
DLK1
反应性
Human
应用
WB,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
41kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human DLK1 expressed in E. Coli.
特异性
DLK1 Monoclonal Antibody detects endogenous levels of DLK1 protein.
基因名称
DLK1
蛋白名称
Protein delta homolog 1
别名
DLK1;DLK;Protein delta homolog 1;DLK-1;pG2
Organism-1
Human
基因ID-1
8788
SwissProt-1
P80370
Organism-2
Mouse
SwissProt-2
Q09163
背景
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015],
细胞定位
Membrane; Single-pass type I membrane protein. Cytoplasm .





