- 产品信息
商品描述
靶点-Target
Dkk-3
反应性
Human,Monkey
应用
WB,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
38kD
推荐稀释比
WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Dkk-3 expressed in E. Coli.
特异性
Dkk-3 Monoclonal Antibody detects endogenous levels of Dkk-3 protein.
基因名称
DKK3
蛋白名称
Dickkopf-related protein 3
别名
DKK3;REIC;Dickkopf-related protein 3;Dickkopf-3;Dkk-3;hDkk-3
Organism-1
Human
基因ID-1
27122
SwissProt-1
Q9UBP4
Organism-2
Mouse
SwissProt-2
Q9QUN9
背景
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.





