FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DDR1
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
101kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of DDR1 (aa602-681) expressed in E. Coli.
特异性
DDR1 Monoclonal Antibody detects endogenous levels of DDR1 protein.
基因名称
DDR1
蛋白名称
Epithelial discoidin domain-containing receptor 1
别名
DDR1;CAK;EDDR1;NEP;NTRK4;PTK3A;RTK6;TRKE;Epithelial discoidin domain-containing receptor 1;Epithelial discoidin domain receptor 1;CD167 antigen-like family member A;Cell adhesion kinase;Discoidin receptor tyrosine kinase;HGK2;
Organism-1
Human
基因ID-1
780
SwissProt-1
Q08345
Organism-2
Mouse
SwissProt-2
Q03146
背景
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011],
细胞定位
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted .; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.
