FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Crk-L
反应性
Human
应用
WB,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
34kD
推荐稀释比
WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Crk-L expressed in E. Coli.
特异性
Crk-L Monoclonal Antibody detects endogenous levels of Crk-L protein.
基因名称
CRKL
蛋白名称
Crk-like protein
别名
CRKL;Crk-like protein
Organism-1
Human
基因ID-1
1399
SwissProt-1
P46109
Organism-2
Mouse
SwissProt-2
P47941
背景
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009],
细胞定位
endosome,cytosol,cell-cell adherens junction,extracellular exosome,
