- 产品信息
商品描述
靶点-Target
Cripto
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
21kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Cripto expressed in E. Coli.
特异性
Cripto Monoclonal Antibody detects endogenous levels of Cripto protein.
基因名称
TDGF1
蛋白名称
Teratocarcinoma-derived growth factor 1
别名
TDGF1;CRIPTO;Teratocarcinoma-derived growth factor 1;Cripto-1 growth factor;CRGF;Epidermal growth factor-like cripto protein CR1
Organism-1
Human
基因ID-1
6997
SwissProt-1
P13385
Organism-2
Mouse
SwissProt-2
P51865
背景
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor . Secreted . Released from the cell membrane by GPI cleavage. .





