FGF-2 Polyclonal Antibody
¥680.00
Chitotriosidase Monoclonal Antibody
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2600554
- 产品信息
商品描述
靶点-Target
Chitotriosidase
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
52kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of Chitotriosidase (aa22-137) expressed in E. Coli.
特异性
Chitotriosidase Monoclonal Antibody detects endogenous levels of Chitotriosidase protein.
基因名称
CHIT1
蛋白名称
Chitotriosidase-1
别名
CHIT1;Chitotriosidase-1;Chitinase-1
Organism-1
Human
基因ID-1
1118
SwissProt-1
Q13231
Organism-2
Mouse
SwissProt-2
Q9D7Q1
背景
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012],
细胞定位
Secreted. Lysosome. A small proportion is lysosomal.
