FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD38
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
34kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human CD38 expressed in E. Coli.
特异性
CD38 Monoclonal Antibody detects endogenous levels of CD38 protein.
基因名称
CD38
蛋白名称
ADP-ribosyl cyclase 1
别名
CD38;ADP-ribosyl cyclase 1;Cyclic ADP-ribose hydrolase 1;cADPr hydrolase 1;T10;CD antigen CD38
Organism-1
Human
基因ID-1
952
SwissProt-1
P28907
Organism-2
Mouse
SwissProt-2
P56528
背景
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
细胞定位
Membrane; Single-pass type II membrane protein.
