FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD1A
反应性
Human
应用
WB,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
37kD
推荐稀释比
WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human CD1A expressed in E. Coli.
特异性
CD1A Monoclonal Antibody detects endogenous levels of CD1A protein.
基因名称
CD1A
蛋白名称
T-cell surface glycoprotein CD1a
别名
CD1A;T-cell surface glycoprotein CD1a;T-cell surface antigen T6/Leu-6;hTa1 thymocyte antigen;CD antigen CD1a
Organism-1
Human
基因ID-1
909
SwissProt-1
P06126
背景
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Subject to intracellular trafficking between the cell membrane and endosomes (PubMed:11231314). Localizes to cell surface lipid rafts (PubMed:18178838). .
