FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CBX1
反应性
Human,Monkey
应用
WB,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
21kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human CBX1 expressed in E. Coli.
特异性
CBX1 Monoclonal Antibody detects endogenous levels of CBX1 protein.
基因名称
CBX1
蛋白名称
Chromobox protein homolog 1
别名
CBX1;CBX;Chromobox protein homolog 1;HP1Hsbeta;Heterochromatin protein 1 homolog beta;HP1 beta;Heterochromatin protein p25;M31;Modifier 1 protein;p25beta
Organism-1
Human
基因ID-1
10951
SwissProt-1
P83916
Organism-2
Mouse
SwissProt-2
P83917
背景
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Unassociated with chromosomes during mitosis.
