- 产品信息
商品描述
靶点-Target
C/EBP β
反应性
Human
应用
WB,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
36kD
推荐稀释比
WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human C/EBP β expressed in E. Coli.
特异性
C/EBP β Monoclonal Antibody detects endogenous levels of C/EBP β protein.
基因名称
CEBPB
蛋白名称
CCAAT/enhancer-binding protein beta
别名
CEBPB;LAP;TCF5;PP9092;CCAAT/enhancer-binding protein beta;C/EBP beta;Liver activator protein;Nuclear factor NF-IL6;Transcription factor 5;TCF-5
Organism-1
Human
基因ID-1
1051
SwissProt-1
P17676
Organism-2
Mouse
SwissProt-2
P28033
背景
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013],
细胞定位
Nucleus . Cytoplasm . Translocates to the nucleus when phosphorylated at Ser-288. In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity). .





