- 产品信息
商品描述
靶点-Target
BNP
反应性
Human
应用
IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
推荐稀释比
IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP, conjugated to KLH.
特异性
BNP Monoclonal Antibody detects endogenous levels of BNP protein.
基因名称
NPPB
蛋白名称
Natriuretic peptides B
别名
NPPB;Natriuretic peptides B;Gamma-brain natriuretic peptide
Organism-1
Human
基因ID-1
4879
SwissProt-1
P16860
Organism-2
Mouse
SwissProt-2
P40753
背景
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014],
细胞定位
[NT-proBNP]: Secreted . Detected in blood. .; [proBNP(3-108)]: Secreted . Detected in blood. .; [Brain natriuretic peptide 32]: Secreted . Detected in blood. .; [BNP(3-32)]: Secreted . Detected in blood. .





