- 产品信息
商品描述
靶点-Target
ETK
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
78kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Bmx expressed in E. Coli.
特异性
Bmx Monoclonal Antibody detects endogenous levels of Bmx protein.
基因名称
BMX
蛋白名称
Cytoplasmic tyrosine-protein kinase BMX
别名
BMX;Cytoplasmic tyrosine-protein kinase BMX;Bone marrow tyrosine kinase gene in chromosome X protein;Epithelial and endothelial tyrosine kinase;ETK;NTK38
Organism-1
Human
基因ID-1
660
SwissProt-1
P51813
Organism-2
Mouse
SwissProt-2
P97504
背景
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],
细胞定位
Cytoplasm . Localizes to the edges of spreading cells when complexed with BCAR1.





