FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BMP-4
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
47kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human BMP-4 expressed in E. Coli.
特异性
BMP-4 Monoclonal Antibody detects endogenous levels of BMP-4 protein.
基因名称
BMP4
蛋白名称
Bone morphogenetic protein 4
别名
BMP4;BMP2B;DVR4;Bone morphogenetic protein 4;BMP-4;Bone morphogenetic protein 2B;BMP-2B
Organism-1
Human
基因ID-1
652
SwissProt-1
P12644
Organism-2
Mouse
SwissProt-2
P21275
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016],
细胞定位
Secreted, extracellular space, extracellular matrix.
