FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Bmi-1
反应性
Human
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
37kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Bmi-1 expressed in E. Coli.
特异性
Bmi-1 Monoclonal Antibody detects endogenous levels of Bmi-1 protein.
基因名称
BMI1
蛋白名称
Polycomb complex protein BMI-1
别名
BMI1;PCGF4;RNF51;Polycomb complex protein BMI-1;Polycomb group RING finger protein 4;RING finger protein 51
Organism-1
Human
基因ID-1
648
SwissProt-1
P35226
Organism-2
Mouse
SwissProt-2
P25916
背景
BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],
细胞定位
Nucleus . Cytoplasm .
