- 产品信息
商品描述
靶点-Target
BLK
反应性
Human
应用
WB,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
58kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Blk expressed in E. Coli.
特异性
Blk Monoclonal Antibody detects endogenous levels of Blk protein.
基因名称
BLK
蛋白名称
Tyrosine-protein kinase Blk
别名
BLK;Tyrosine-protein kinase Blk;B lymphocyte kinase;p55-Blk
Organism-1
Human
基因ID-1
640
SwissProt-1
P51451
Organism-2
Mouse
SwissProt-2
P16277
背景
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],
细胞定位
Cell membrane ; Lipid-anchor . Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity). .





