- 产品信息
商品描述
靶点-Target
Axl
反应性
Human
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant extracellular fragment of human Axl fused with hIgGFc tag expressed in HEK293 cell line.
特异性
Axl Monoclonal Antibody detects endogenous levels of Axl protein.
基因名称
AXL UFO
蛋白名称
Tyrosine-protein kinase receptor UFO
别名
AXL;UFO;Tyrosine-protein kinase receptor UFO;AXL oncogene
Organism-1
Human
基因ID-1
558
SwissProt-1
P30530
Organism-2
Mouse
SwissProt-2
Q00993
背景
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
细胞定位
Cell membrane ; Single-pass type I membrane protein .





