Axl Monoclonal Antibody

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2600484

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商品描述
  • 靶点-Target

    Axl

  • 反应性

    Human

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    130kD

  • 推荐稀释比

    WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    Affinity purification

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 免疫原

    Purified recombinant extracellular fragment of human Axl fused with hIgGFc tag expressed in HEK293 cell line.

  • 特异性

    Axl Monoclonal Antibody detects endogenous levels of Axl protein.

  • 基因名称

    AXL UFO

  • 蛋白名称

    Tyrosine-protein kinase receptor UFO

  • 别名

    AXL;UFO;Tyrosine-protein kinase receptor UFO;AXL oncogene

  • Organism-1

    Human

  • 基因ID-1

    558

  • SwissProt-1

    P30530

  • Organism-2

    Mouse

  • SwissProt-2

    Q00993

  • 背景

    The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],

  • 细胞定位

    Cell membrane ; Single-pass type I membrane protein .