FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Axl
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of Axl (aa466-530) expressed in E. Coli.
特异性
Axl Monoclonal Antibody detects endogenous levels of Axl protein.
基因名称
AXL UFO
蛋白名称
Tyrosine-protein kinase receptor UFO
别名
AXL;UFO;Tyrosine-protein kinase receptor UFO;AXL oncogene
Organism-1
Human
基因ID-1
558
SwissProt-1
P30530
Organism-2
Mouse
SwissProt-2
Q00993
背景
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
