FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Ataxin-1
反应性
Human
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
87kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Ataxin-1 expressed in E. Coli.
特异性
Ataxin-1 Monoclonal Antibody detects endogenous levels of Ataxin-1 protein.
基因名称
ATXN1
蛋白名称
Ataxin-1
别名
ATXN1;ATX1;SCA1;Ataxin-1;Spinocerebellar ataxia type 1 protein
Organism-1
Human
基因ID-1
6310
SwissProt-1
P54253
Organism-2
Mouse
SwissProt-2
P54254
背景
ataxin 1(ATXN1) Homo sapiens The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted
细胞定位
Cytoplasm . Nucleus . Colocalizes with USP7 in the nucleus. .
