- 产品信息
商品描述
靶点-Target
Arg
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
128kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of Arg expressed in E. Coli.
特异性
Arg Monoclonal Antibody detects endogenous levels of Arg protein.
基因名称
ABL2
蛋白名称
Tyrosine-protein kinase ABL2
别名
ABL2;ABLL;ARG;Abelson tyrosine-protein kinase 2;Abelson murine leukemia viral oncogene homolog 2;Abelson-related gene protein;Tyrosine-protein kinase ARG
Organism-1
Human
基因ID-1
27
SwissProt-1
P42684
Organism-2
Mouse
SwissProt-2
Q4JIM5
背景
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009],
细胞定位
Cytoplasm, cytoskeleton.





