FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ApoA-V
反应性
Human
应用
ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
推荐稀释比
ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human ApoA-V expressed in E. Coli.
特异性
ApoA-V(bd) Monoclonal Antibody detects endogenous levels of ApoA-V(bd) protein.
基因名称
APOA5
蛋白名称
Apolipoprotein A-V
别名
APOA5;RAP3;Apolipoprotein A-V;Apo-AV;ApoA-V;Apolipoprotein A5;Regeneration-associated protein 3
Organism-1
Human
基因ID-1
116519
SwissProt-1
Q6Q788
Organism-2
Mouse
SwissProt-2
Q8C7G5
背景
The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009],
细胞定位
Secreted . Early endosome . Late endosome . Golgi apparatus, trans-Golgi network . In the presence of SORL1, internalized to early endosomes, sorted in a retrograde fashion to late endosomes, from which a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network. .
