- 产品信息
商品描述
靶点-Target
ApoA-I
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
31kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human ApoA-I expressed in E. Coli.
特异性
ApoA-I Monoclonal Antibody detects endogenous levels of ApoA-I protein.
基因名称
APOA1
蛋白名称
Apolipoprotein A-I
别名
APOA1;Apolipoprotein A-I;Apo-AI;ApoA-I;Apolipoprotein A1
Organism-1
Human
基因ID-1
335
SwissProt-1
P02647
Organism-2
Mouse
SwissProt-2
Q00623
背景
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015],
细胞定位
Secreted.





