FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AGT
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
52kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human AGT expressed in E. Coli.
特异性
AGT Monoclonal Antibody detects endogenous levels of AGT protein.
基因名称
AGT
蛋白名称
Angiotensinogen
别名
AGT;SERPINA8;Angiotensinogen;Serpin A8
Organism-1
Human
基因ID-1
183
SwissProt-1
P01019
Organism-2
Mouse
SwissProt-2
P11859
背景
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.
