- 产品信息
商品描述
靶点-Target
AATM
反应性
Human,Mouse,Rat,Monkey
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
48kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human AATM expressed in E. Coli.
特异性
AATM Monoclonal Antibody detects endogenous levels of AATM protein.
基因名称
GOT2
蛋白名称
Aspartate aminotransferase, mitochondrial
别名
GOT2;Aspartate aminotransferase;mitochondrial;mAspAT;Fatty acid-binding protein;FABP-1;Glutamate oxaloacetate transaminase 2;Kynurenine aminotransferase 4;Kynurenine aminotransferase IV;Kynurenine--oxoglutarate transaminase 4;Kynu
Organism-1
Human
基因ID-1
2806
SwissProt-1
P00505
Organism-2
Mouse
基因ID-2
14719
SwissProt-2
P05202
Organism-3
Rat
基因ID-3
25721
SwissProt-3
P00507
背景
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013],
细胞定位
Mitochondrion matrix . Cell membrane . Exposure to alcohol promotes translocation to the cell membrane. .





