- 产品信息
商品描述
靶点-Target
Histone H2A.Z
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
14kD
推荐稀释比
WB 1:500-1000
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Synthetic Peptide of Histone H2A.Z (Acetyl Lys7)
特异性
The antibody detects endogenous Histone H2A.Z (Acetyl Lys7) protein.
基因名称
H2AFZ
蛋白名称
Histone H2A.Z
别名
H2AFZ;H2AZ;Histone H2A.Z;H2A/z
Organism-1
Human
基因ID-1
3015
SwissProt-1
P0C0S5
Organism-2
Mouse
基因ID-2
51788
SwissProt-2
P0C0S6
Organism-3
Rat
基因ID-3
58940
SwissProt-3
P0C0S7
背景
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Chromosome.





