Sp3 (Acetyl Lys551) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600418
- 产品信息
商品描述
靶点-Target
Sp3
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
85kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Sp3 (Acetyl Lys551)
特异性
This antibody detects endogenous levels of Human,Mouse Sp3 (Acetyl Lys551)
基因名称
SP3
蛋白名称
Sp3 (Acetyl Lys551)
别名
Transcription factor Sp3;SPR-2;
Organism-1
Human
基因ID-1
6670
SwissProt-1
Q02447
Organism-2
Mouse
基因ID-2
20687
SwissProt-2
O70494
背景
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq, Feb 2010],
细胞定位
Nucleus. Nucleus, PML body. Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies.





