FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Sp1
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
90kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Sp1 (Acetyl Lys703)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat Sp1 (Acetyl Lys703)
基因名称
SP1 TSFP1
蛋白名称
Sp1 (Acetyl Lys703)
别名
Transcription factor Sp1
Organism-1
Human
基因ID-1
6667
SwissProt-1
P08047
Organism-2
Mouse
基因ID-2
20683
SwissProt-2
O89090
Organism-3
Rat
基因ID-3
24790
SwissProt-3
Q01714
背景
function:Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.,PTM:O-glycosylated; contains N-acetylglucosamine side chains.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with ATF7IP, ATF7IP2, POGZ, HCFC1, AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.,
细胞定位
Nucleus. Cytoplasm. Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location.
