Smad2/3 (Acetyl Lys420/378) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600415
- 产品信息
商品描述
靶点-Target
Smad2/3
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
55kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Smad2/3 (Acetyl Lys420/378)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat Smad2/3 (Acetyl Lys420/378)
基因名称
SMAD2 MADH2 MADR2
蛋白名称
Smad2/3 (Acetyl Lys420/378)
别名
Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2;
Organism-1
Human
基因ID-1
4087
SwissProt-1
Q15796;P84022
Organism-2
Mouse
基因ID-2
17126
SwissProt-2
Q62432
Organism-3
Rat
基因ID-3
29357
SwissProt-3
O70436
细胞定位
Cytoplasm . Nucleus . Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:9865696, PubMed:21145499). On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD4 complex, and exported out of the nucleus by interaction with RANBP1 (PubMed:16751101, PubMed:19289081). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .





