FGF-2 Polyclonal Antibody
¥680.00
p21 (Acetyl Lys154) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
一键复制产品信息
产品规格：
- 50μL
- 100μL
货号：
FAB2600411
- 产品信息
商品描述
靶点-Target
p21
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
21kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human p21 (Acetyl Lys154)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat p21 (Acetyl Lys154)
基因名称
CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1
蛋白名称
p21 (Acetyl Lys154)
别名
Cyclin-dependent kinase inhibitor 1;CDK-interacting protein 1;Melanoma differentiation-associated protein 6;MDA-6;p21;
Organism-1
Human
基因ID-1
1026
SwissProt-1
P38936
Organism-2
Mouse
基因ID-2
12575
SwissProt-2
P39689
背景
function:May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.,induction:By p53, mezerein (antileukemic compound) and interferon beta.,PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in all adult human tissues, with 5-fold lower levels observed in the brain.,
细胞定位
Cytoplasm . Nucleus .
