FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
c-Myc
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
55kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human c-Myc (Acetyl Lys148)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat c-Myb (Acetyl Lys148)
基因名称
MYC BHLHE39
蛋白名称
c-Myc (Acetyl Lys148)
别名
Myc proto-oncogene protein;Class E basic helix-loop-helix protein 39;bHLHe39;Proto-oncogene c-Myc;Transcription factor p64;
Organism-1
Human
基因ID-1
4609
SwissProt-1
P01106
Organism-2
Mouse
基因ID-2
17869
SwissProt-2
P01108
Organism-3
Rat
基因ID-3
24577
SwissProt-3
P09416
背景
disease:A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with BTG1.,disease:Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors.,function:Participates in the regulation of gene transcription. Binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.,online information:Myc entry,PTM:Phosphorylated by PRKDC.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C and SPAG9. Interacts with PARP10. Interacts with KDM5A and KDM5B.,
细胞定位
Nucleus, nucleoplasm . Nucleus, nucleolus .
