FGF-2 Polyclonal Antibody
¥680.00
Rb (Acetyl-K873/K874) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2600340
- 产品信息
商品描述
靶点-Target
Rb
反应性
Human:K873+K874,Mouse:K866+K867,Rat:K865+K866
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Calculated)
106kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized Acetyl peptide derived from human Rb. at AA range: K873/872
特异性
This antibody detects endogenous levels of Rb at Human:K873+K874;Mouse:K866+K867;Rat:K865+K866, It doesn't reacte with total protein.
基因名称
RB1
蛋白名称
Rb
别名
Retinoblastoma-associated protein;p105-Rb;pRb;Rb;pp110;
Organism-1
Human
基因ID-1
5925
SwissProt-1
P06400
Organism-2
Mouse
SwissProt-2
P13405
背景
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . During keratinocyte differentiation, acetylation by KAT2B/PCAF is required for nuclear localization. .
