HNF-4α/γ (Acetyl Lys127/79) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2600330

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商品描述
  • 靶点-Target

    HNF-4α/γ

  • 反应性

    Human:K127/79,Mouse:K127/79,Rat:K127

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Acetyl

  • MW(Observed)

    55kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:10000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic Acetyl peptide from human protein at AA range: 127(HNF-4α)/79(HNF-4γ)

  • 特异性

    This antibody detects endogenous levels of HNF-4α/γ at Human:K127/79;Mouse:K127/79;Rat:K127, It doesn't reacte with total protein.

  • 基因名称

    HNF4A HNF4 NR2A1 TCF14 HNF4G NR2A2

  • 蛋白名称

    Hepatocyte nuclear factor 4-alpha/gamma (HNF-4-alpha/gamma) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)

  • 别名

    Hepatocyte nuclear factor 4-alpha;HNF-4-alpha;Nuclear receptor subfamily 2 group A member 1;Transcription factor 14;Hepatocyte nuclear factor 4-gamma;HNF-4-gamma;Nuclear receptor subfamily 2 group A member 2;TCF-14;Transcription factor HNF-4;

  • Organism-1

    Human

  • 基因ID-1

    3172

  • SwissProt-1

    P41235;Q14541

  • 背景

    The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],

  • 细胞定位

    Nucleus.