FoxO4 (Acetyl Lys189) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600326
- 产品信息
商品描述
靶点-Target
FoxO4
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
55kD
推荐稀释比
WB 1:500-2000;ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Acetyl peptide from human protein at AA range: 189
特异性
The antibody detects endogenous FoxO4 when Acetyl occurs at Lys189
基因名称
FOXO4 AFX AFX1 MLLT7
蛋白名称
Forkhead box protein O4 (Fork head domain transcription factor AFX1)
别名
Forkhead box protein O4;Fork head domain transcription factor AFX1;
Organism-1
Human
基因ID-1
4303
SwissProt-1
P98177
Organism-2
Mouse
SwissProt-2
Q9WVH3
背景
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
细胞定位
Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.





