E2F-3 (Acetyl Lys168) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2600323

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商品描述
  • 靶点-Target

    E2F-3

  • 反应性

    Human:K168,Mouse:K160,Rat:K161

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Acetyl

  • MW(Observed)

    50kD

  • 推荐稀释比

    WB 1:500-10000;ELISA 1:10000

  • 组成

    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized acetyl-peptide from human protein at AA range: 130-200

  • 特异性

    This antibody detects endogenous levels of E2F-3 at Human:K168;Mouse:K160;Rat:K161, It doesn't reacte with total protein.

  • 基因名称

    E2F3 KIAA0075

  • 蛋白名称

    E2F transcription factor 3

  • 别名

    E2F3 KIAA0075

  • Organism-1

    Human

  • 基因ID-1

    1871

  • SwissProt-1

    O00716

  • Organism-2

    Mouse

  • SwissProt-2

    O35261

  • 背景

    This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013],

  • 细胞定位

    Nucleus.