E2F-3 (Acetyl Lys168) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600323
- 产品信息
商品描述
靶点-Target
E2F-3
反应性
Human:K168,Mouse:K160,Rat:K161
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
50kD
推荐稀释比
WB 1:500-10000;ELISA 1:10000
组成
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized acetyl-peptide from human protein at AA range: 130-200
特异性
This antibody detects endogenous levels of E2F-3 at Human:K168;Mouse:K160;Rat:K161, It doesn't reacte with total protein.
基因名称
E2F3 KIAA0075
蛋白名称
E2F transcription factor 3
别名
E2F3 KIAA0075
Organism-1
Human
基因ID-1
1871
SwissProt-1
O00716
Organism-2
Mouse
SwissProt-2
O35261
背景
This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013],
细胞定位
Nucleus.





