FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
E2F-1
反应性
Human:K120,Mouse:K115,Rat:K118
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
60kD
推荐稀释比
WB 1:500-10000;ELISA 1:10000
组成
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized acetyl-peptide from human protein at AA range: 100-170
特异性
This antibody detects endogenous levels of E2F-1 at Human:K120;Mouse:K115;Rat:K118, It doesn't reacte with total protein.
基因名称
E2F1 RBBP3
蛋白名称
E2F transcription factor 1
别名
E2F1 RBBP3
Organism-1
Human
基因ID-1
1869
SwissProt-1
Q01094
Organism-2
Mouse
SwissProt-2
Q61501
Organism-3
Rat
SwissProt-3
O09139
背景
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media
细胞定位
Nucleus .
