FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
14-3-3-pan
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
30kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized acetyl-peptide derived from human 14-3-3-pan around the acetylation site of K51.
特异性
Acetyl-14-3-3-pan (K51/49) Polyclonal Antibody detects endogenous levels of 14-3-3-pan around the acetylation site of K51 protein.
基因名称
YWHAB/YWHAG/YWHAQ/YWHAZ/SFN
蛋白名称
14-3-3 protein beta/alpha/14-3-3 protein gamma/14-3-3 protein theta/14-3-3 protein zeta/delta/14-3-3 protein sigma
别名
YWHAB;14-3-3 protein beta/alpha;Protein 1054;Protein kinase C inhibitor protein 1;KCIP-1;YWHAG;14-3-3 protein gamma;Protein kinase C inhibitor protein 1;KCIP-1;YWHAQ;14-3-3 protein theta;14-3-3 protein T-cell;14-3-3 protein tau;Protein HS1;YWHAZ;14-3-3 protein zeta/delta;Protein kinase C inhibitor protein 1;KCIP-1;SFN;HME1;14-3-3 protein sigma;Epithelial cell marker protein 1;Stratifin
Organism-1
Human
基因ID-1
7529
SwissProt-1
P31946
Organism-2
Mouse
基因ID-2
54401
SwissProt-2
Q9CQV8
Organism-3
Rat
基因ID-3
56011
SwissProt-3
P35213
背景
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.; Vacuole membrane . (Microbial infection) Upon infection with Chlamydia trachomatis, this protein is associated with the pathogen-containing vacuole membrane where it colocalizes with IncG. .
