CRM1 (Acetyl Lys568) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600306
- 产品信息
商品描述
靶点-Target
CRM1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
125kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.
特异性
Acetyl-CRM1 (K568) Polyclonal Antibody detects endogenous levels of CRM1 protein only when acetylation at K568.
基因名称
XPO1
蛋白名称
Exportin-1
别名
XPO1;CRM1;Exportin-1;Exp1;Chromosome region maintenance 1 protein homolog
Organism-1
Human
基因ID-1
7514
SwissProt-1
O14980
Organism-2
Mouse
基因ID-2
103573
SwissProt-2
Q6P5F9
Organism-3
Rat
基因ID-3
85252
SwissProt-3
Q80U96
背景
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],
细胞定位
Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.





