FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Tubulin α
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Acetyl
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized acetyl-peptide derived from human Tubulin α around the acetylation site of K112.
特异性
Acetyl-Tubulin α (K112) Polyclonal Antibody detects endogenous levels of Tubulin α protein only when acetylated at K112.
基因名称
TUBA1A/TUBA1B/TUBA1C
蛋白名称
Tubulin alpha-1A chain/Tubulin alpha-1B chain/Tubulin alpha-1C chain
别名
TUBA1A;TUBA3;Tubulin alpha-1A chain;Alpha-tubulin 3;Tubulin B-alpha-1;Tubulin alpha-3 chain;TUBA1B;Tubulin alpha-1B chain;Alpha-tubulin ubiquitousTubulin K-alpha-1;Tubulin alpha-ubiquitous chain;TUBA1C;TUBA6;Tubulin alpha-1C chain;Alpha-tubulin 6;Tubulin alpha-6 chain
Organism-1
Human
基因ID-1
7846;10376;84790
SwissProt-1
Q71U36;P68363;Q9BQE3
Organism-2
Mouse
基因ID-2
22142;22143;22146
Organism-3
Rat
基因ID-3
64158;500929;100909441
SwissProt-3
P68370;Q6P9V9;Q6AYZ1
背景
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
细胞定位
Cytoplasm, cytoskeleton.
