p73 (Acetyl Lys321) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2600285

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商品描述
  • 靶点-Target

    p73

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Acetyl

  • MW(Observed)

    70kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized Acetyl-peptide derived from human p73 around the Acetylation site of Lys321. AA range:281-330

  • 特异性

    Acetyl-p73 (K321) Polyclonal Antibody detects endogenous levels of p73 protein only when acetylated at K321.

  • 基因名称

    TP73

  • 蛋白名称

    Tumor protein p73

  • 别名

    TP73;P73;Tumor protein p73;p53-like transcription factor;p53-related protein

  • Organism-1

    Human

  • 基因ID-1

    7161

  • SwissProt-1

    O15350

  • Organism-2

    Mouse

  • SwissProt-2

    Q9JJP2

  • 背景

    tumor protein p73(TP73) Homo sapiens This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011],

  • 细胞定位

    Nucleus . Cytoplasm. Accumulates in the nucleus in response to DNA damage.