FGF-2 Polyclonal Antibody
¥680.00
NOTCH4 (Cleaved-Val1467) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
一键复制产品信息
产品规格：
- 50μL
- 100μL
货号：
FAB2600195
- 产品信息
商品描述
靶点-Target
Notch 4
反应性
Human,Monkey
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD,220kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NOTCH4 (Cleaved-Val1467)
特异性
This antibody detects endogenous levels of Human,Monkey NOTCH4 (Cleaved-Val1467, protein was cleaved amino acid sequence between 1466-1467 )
基因名称
NOTCH4 INT3
蛋白名称
NOTCH4 (Cleaved-Val1467)
别名
Neurogenic locus notch homolog protein 4;Notch 4;hNotch4;[Cleaved into: Notch 4 extracellular truncation;Notch 4 intracellular domain]
Organism-1
Human
基因ID-1
4855
SwissProt-1
Q99466
Organism-2
Mouse
基因ID-2
18132
SwissProt-2
P31695
背景
notch 4(NOTCH4) Homo sapiens This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which
细胞定位
Cell membrane; Single-pass type I membrane protein.; [Notch 4 intracellular domain]: Nucleus. Following proteolytical processing NICD is translocated to the nucleus.
