- 产品信息
商品描述
靶点-Target
PERM
反应性
Human,Rat,Mouse,
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
12kD,84kD,89kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PERM (light chain, Cleaved-Gly278)
特异性
This antibody detects endogenous levels of Human PERM (light chain, Cleaved-Gly278, protein was cleaved amino acid sequence between 278-279 )
基因名称
MPO
蛋白名称
PERM (light chain, Cleaved-Gly278)
别名
Myeloperoxidase;MPO;[Cleaved into: Myeloperoxidase;89 kDa myeloperoxidase;84 kDa myeloperoxidase;Myeloperoxidase light chain;Myeloperoxidase heavy chain]
Organism-1
Human
基因ID-1
4353
SwissProt-1
P05164
Organism-2
Mouse
基因ID-2
17523
SwissProt-2
P11247
背景
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014],
细胞定位
Lysosome.





