PERM (light chain, Cleaved-Gly278) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2600187

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商品描述
  • 靶点-Target

    PERM

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    12kD,84kD,89kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human PERM (light chain, Cleaved-Gly278)

  • 特异性

    This antibody detects endogenous levels of Human PERM (light chain, Cleaved-Gly278, protein was cleaved amino acid sequence between 278-279 )

  • 基因名称

    MPO

  • 蛋白名称

    PERM (light chain, Cleaved-Gly278)

  • 别名

    Myeloperoxidase;MPO;[Cleaved into: Myeloperoxidase;89 kDa myeloperoxidase;84 kDa myeloperoxidase;Myeloperoxidase light chain;Myeloperoxidase heavy chain]

  • Organism-1

    Human

  • 基因ID-1

    4353

  • SwissProt-1

    P05164

  • Organism-2

    Mouse

  • 基因ID-2

    17523

  • SwissProt-2

    P11247

  • 背景

    Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014],

  • 细胞定位

    Lysosome.