ITGAV (light chain, Cleaved-Asp891) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600167
- 产品信息
商品描述
靶点-Target
ITGAV
反应性
Human,Mouse
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
17kD,110kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ITGAV (light chain, Cleaved-Asp891)
特异性
This antibody detects endogenous levels of Human,Mouse ITGAV (light chain, Cleaved-Asp891, protein was cleaved amino acid sequence between 890-891 )
基因名称
ITGAV MSK8 VNRA
蛋白名称
ITGAV (light chain, Cleaved-Asp891)
别名
Integrin alpha-V;Vitronectin receptor subunit alpha;CD antigen CD51;[Cleaved into: Integrin alpha-V heavy chain;Integrin alpha-V light chain]
Organism-1
Human
基因ID-1
3685
SwissProt-1
P06756
Organism-2
Mouse
基因ID-2
16410
SwissProt-2
P43406
背景
integrin subunit alpha V(ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],
细胞定位
Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion .





