ITGAV (light chain, Cleaved-Asp891) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2600167

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商品描述
  • 靶点-Target

    ITGAV

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    17kD,110kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human ITGAV (light chain, Cleaved-Asp891)

  • 特异性

    This antibody detects endogenous levels of Human,Mouse ITGAV (light chain, Cleaved-Asp891, protein was cleaved amino acid sequence between 890-891 )

  • 基因名称

    ITGAV MSK8 VNRA

  • 蛋白名称

    ITGAV (light chain, Cleaved-Asp891)

  • 别名

    Integrin alpha-V;Vitronectin receptor subunit alpha;CD antigen CD51;[Cleaved into: Integrin alpha-V heavy chain;Integrin alpha-V light chain]

  • Organism-1

    Human

  • 基因ID-1

    3685

  • SwissProt-1

    P06756

  • Organism-2

    Mouse

  • 基因ID-2

    16410

  • SwissProt-2

    P43406

  • 背景

    integrin subunit alpha V(ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],

  • 细胞定位

    Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion .