ITGA2B (heavy chain, Cleaved-Leu32) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600165
- 产品信息
商品描述
靶点-Target
CD41
反应性
Human,Rat,Mouse,
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
95kD,110kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ITGA2B (heavy chain, Cleaved-Leu32)
特异性
This antibody detects endogenous levels of Human ITGA2B (heavy chain, Cleaved-Leu32, protein was cleaved amino acid sequence between 31-32 )
基因名称
ITGA2B GP2B ITGAB
蛋白名称
ITGA2B (heavy chain, Cleaved-Leu32)
别名
Integrin alpha-IIb;GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD antigen CD41;[Cleaved into: Integrin alpha-IIb heavy chain;Integrin alpha-IIb light chain, form 1;Integrin alpha-IIb light chain, form 2]
Organism-1
Human
基因ID-1
3674
SwissProt-1
P08514
Organism-2
Mouse
基因ID-2
16399
SwissProt-2
Q9QUM0
背景
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],
细胞定位
Membrane; Single-pass type I membrane protein.





