- 产品信息
商品描述
靶点-Target
ITGAE
反应性
Human,Rat,Mouse,
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
110kD,128kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ITGAE (heavy chain, Cleaved-Ala179)
特异性
This antibody detects endogenous levels of Human ITGAE (heavy chain, Cleaved-Ala179, protein was cleaved amino acid sequence between 178-179 )
基因名称
ITGAE
蛋白名称
ITGAE (heavy chain, Cleaved-Ala179)
别名
Integrin alpha-E;HML-1 antigen;Integrin alpha-IEL;Mucosal lymphocyte 1 antigen;CD antigen CD103;[Cleaved into: Integrin alpha-E light chain;Integrin alpha-E heavy chain]
Organism-1
Human
基因ID-1
3682
SwissProt-1
P38570
Organism-2
Mouse
基因ID-2
16407
SwissProt-2
Q60677
背景
integrin subunit alpha E(ITGAE) Homo sapiens Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008],
细胞定位
Membrane; Single-pass type I membrane protein.





