FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Integrin α3
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
93kD,115kD
推荐稀释比
WB 1:500-2000;IF/ICC1:50-200;ELISA 1:2000-20000;IHC 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ITGA3 (heavy chain, Cleaved-Phe33)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat ITGA3 (heavy chain, Cleaved-Phe33, protein was cleaved amino acid sequence between 32-33 )
基因名称
ITGA3 MSK18
蛋白名称
ITGA3 (heavy chain, Cleaved-Phe33)
别名
Integrin alpha-3;CD49 antigen-like family member C;FRP-2;Galactoprotein B3;GAPB3;VLA-3 subunit alpha;CD antigen CD49c;[Cleaved into: Integrin alpha-3 heavy chain;Integrin alpha-3 light chain]
Organism-1
Human
基因ID-1
3675
SwissProt-1
P26006
Organism-2
Mouse
基因ID-2
16400
SwissProt-2
Q62470
背景
integrin subunit alpha 3(ITGA3) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor . Cell projection, invadopodium membrane ; Single-pass type I membrane protein . Cell projection, filopodium membrane ; Single-pass type I membrane protein . Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner. .
